Impregnation of dimeric CrIII(salen) on silica and its application in epoxide asymmetric ring opening reactions Original Research Article

The heterogeneous asymmetric ring opening (ARO) of epoxides with trimethylsilylazide (TMSN3) catalysed by a dimeric Cr(salen) catalyst impregnated on a silica material combines high enantioselectivities for epoxide and ring opened product with good conversions and suffers only from low leaching in both batch and continuous flow experiments.