Title of article
Understanding enzymic catalysis: the importance of short, strong hydrogen bonds Review Article
Author/Authors
John A. Gerlt، نويسنده , , Maurice M. Kreevoy، نويسنده , , W.W. Cleland، نويسنده , , Perry A. Frey، نويسنده ,
Issue Information
ماهنامه با شماره پیاپی سال 1997
Pages
9
From page
259
To page
267
Abstract
We have proposed previously that short, strong hydrogen bonds exist in enzyme active sites and that they are important in explaining enzymic rate enhancements. Here, we defend this proposal and provide evidence for likely changes of hydrogen bond strengths during enzymic catalysis.
Journal title
Chemistry and Biology
Serial Year
1997
Journal title
Chemistry and Biology
Record number
1157914
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