• Title of article

    Apoptolidin, a selective cytotoxic agent, is an inhibitor of F0F1-ATPase Original Research Article

  • Author/Authors

    Arthur R. Salomon، نويسنده , , David W Voehringer، نويسنده , , Leonard A Herzenberg، نويسنده , , Chaitan Khosla، نويسنده ,

  • Issue Information
    ماهنامه با شماره پیاپی سال 2001
  • Pages
    10
  • From page
    71
  • To page
    80
  • Abstract
    Background: Apoptolidin is a macrolide originally identified on the basis of its ability to selectively kill E1A and E1A/E1B19K transformed rat glial cells while not killing untransformed glial cells. The goal of this study was to identify the molecular target of this newly discovered natural product.
  • Keywords
    Apoptolidin , Apoptotic pathway , macrolide , Mitochondrial F0F1-ATP synthase
  • Journal title
    Chemistry and Biology
  • Serial Year
    2001
  • Journal title
    Chemistry and Biology
  • Record number

    1158339