Title of article
Apoptolidin, a selective cytotoxic agent, is an inhibitor of F0F1-ATPase Original Research Article
Author/Authors
Arthur R. Salomon، نويسنده , , David W Voehringer، نويسنده , , Leonard A Herzenberg، نويسنده , , Chaitan Khosla، نويسنده ,
Issue Information
ماهنامه با شماره پیاپی سال 2001
Pages
10
From page
71
To page
80
Abstract
Background: Apoptolidin is a macrolide originally identified on the basis of its ability to selectively kill E1A and E1A/E1B19K transformed rat glial cells while not killing untransformed glial cells. The goal of this study was to identify the molecular target of this newly discovered natural product.
Keywords
Apoptolidin , Apoptotic pathway , macrolide , Mitochondrial F0F1-ATP synthase
Journal title
Chemistry and Biology
Serial Year
2001
Journal title
Chemistry and Biology
Record number
1158339
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