Title of article
Reflections on a Novel Therapeutic Candidate Review Article
Author/Authors
Letha J Sooter، نويسنده , , Andrew D Ellington، نويسنده ,
Issue Information
ماهنامه با شماره پیاپی سال 2002
Pages
2
From page
857
To page
858
Abstract
Aptamers composed of L-nucleic acids, Spiegelmers, were selected to specifically bind GnRH. Spiegelmer inhibition of GnRH activity was demonstrated in both cellular and animal models. Rabbit studies showed minimal immunogenic response to the agents.
Journal title
Chemistry and Biology
Serial Year
2002
Journal title
Chemistry and Biology
Record number
1158530
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