Title of article
New Insights into Drug Resistance in Cancer Review Article
Author/Authors
Sarah L Monahan، نويسنده , , Henry A Lester، نويسنده , , Dennis A. Dougherty، نويسنده ,
Issue Information
ماهنامه با شماره پیاپی سال 2003
Pages
2
From page
583
To page
584
Abstract
New findings by Kavallaris et al. characterize mechanisms of resistance to epothilones and paclitaxel in cell lines. One significant discovery is a novel tubulin point mutation positioned outside the paclitaxel binding site, which confers a high degree of drug resistance.
Journal title
Chemistry and Biology
Serial Year
2003
Journal title
Chemistry and Biology
Record number
1158664
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