• Title of article

    Optimized Chimeragenesis: Creating Diverse P450 Functions Review Article

  • Author/Authors

    Rita Bernhardt and Udo Heinemann، نويسنده ,

  • Issue Information
    ماهنامه با شماره پیاپی سال 2004
  • Pages
    2
  • From page
    287
  • To page
    288
  • Abstract
    A drawback to generating chimeric proteins by chimeragenesis, especially when the “parent” proteins share low sequence identity, is that unfolded proteins frequently result. In this issue of Chemistry & Biology, Arnold and coworkers report their use of the SCHEMA algorithm to effectively predict ideal hybrids of cytochromes P450 .
  • Journal title
    Chemistry and Biology
  • Serial Year
    2004
  • Journal title
    Chemistry and Biology
  • Record number

    1158787