The Response of Plasma Leptin and Some Selected Hormones to 24-weeks Aerobic Exercise in Inactive Obese Women

Background: Leptin resistance is one of the influential factors on hyperinsulinism and finally on lack of the glucose tolerance in overweight and its related diseases. Thus the goal of this research is to study the response of Leptin Plasma, 17-beta estradiol serum and insulin to 24-weeks aerobic exercise in inactive obese women. Method: The research was of semi-experimental kind. 15 inactive obese women were chosen randomly and were categorized in two different groups; i.e. aerobic exercise and control. The exercise process included aerobic exercises for 6 months (three 60-minute sessions per week).we used repeated measure for variation the time × group. The Independent sample T test was applied to compare the average amounts between groups. Result: The results represent that the influence of time has not been identical on amount of leptin serum, insulin, the body mass index and fat amount, and a 24-weeks aerobic exercise caused a significant decrease in this field (P?0.05). After 24-weeks aerobic exercises, duration of time in two different control and aerobic exercise groups showed no important effect on the level of 17-beta estradiol serum (P = 0.393). Conclusion Results showed that, aerobic exercises reduce the body mass index and consequently reduce leptin and insulin in inactive obese women via increasing the capacity of muscle in using the fat, which can be considered as a preventing factor of obesity and its related diseases, such as obesity and cardiovascular diseases