Title of article
New synthesis of PNA-3DNA linker monomers, useful building blocks to obtain PNA/DNA chimeras
Author/Authors
Pedone، Carlo نويسنده , , Musumeci، Domenica نويسنده , , Roviello، Giovanni N. نويسنده , , Valente، Margherita نويسنده , , Sapio، Roberto نويسنده , , Bucci، Enrico M. نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
-534
From page
535
To page
0
Abstract
A new synthetic strategy to get the PNA-3ʹDNA linker with the monomethoxytrityl (Mmt) group as temporary protection of the backbone to be used for the synthesis of PNA/DNA chimeras was employed and a convenient strategy to obtain Mmt PNA monomers was developed. The synthetic strategies take advantage of the introduction of the acidlabile Mmt-protecting group in the first step.
Keywords
monomethoxytrityl group , peptide nucleic acids , PNA/DNA chimera , PNA-DNA linker
Journal title
BIOPOLYMERS (ORIGINAL RESEARCH ON BIOMOLECULES)
Serial Year
2004
Journal title
BIOPOLYMERS (ORIGINAL RESEARCH ON BIOMOLECULES)
Record number
120804
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