Title of article
Effect of electrostatic interactions on the formation of proton transfer pathways in human carbonic anhydrase II
Author/Authors
ROY، ARIJIT نويسنده , , TARAPHDER، SRABANI نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
8
From page
545
To page
552
Abstract
We report here a theoretical study on the effect of electrostatic interactions on the formation of dynamical, proton-conducting hydrogen-bonded networks in the protein HCA II. The conformational fluctuations of His-64 is found to contribute crucially to the mechanism of such path formation irrespective of the way electrostatic interactions are modelled.
Keywords
protein HCA II , conformational fluctuation , proton conducting , Electrostatic effect
Journal title
Journal of Chemical Sciences
Serial Year
2007
Journal title
Journal of Chemical Sciences
Record number
121800
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