Vasorelaxant Properties of Loranthus ferrugineus Roxb. Methanolic Extract

In the present study, Loranthus ferrugineus was evaluated for blood pressure lowering activity using in vitro and in vivo animal experimental approaches. The fresh aerial parts of the plant were dried, pulverized into powder and successively extracted with petroleum ether, chloroform, ethyl acetate, methanol and water using hot extraction methods. Each of the extracts was dried under reduced pressure using rotary evaporator and subsequently freeze-dried. The effects of three different concentrations (0.5, 1 and 2 mg mL -1 of each extract were examined on isolated rat aortic ring preparations and responses to cumulative doses of noradrenaline (NA) were measured. It was found that the relatively polar methanol extract was the most potent to produce a significant (p