Title of article
New approach to the quaternization of chitosan and its amphiphilic derivatives
Author/Authors
Evgeniya A. Stepnova، نويسنده , , Vladimir E. Tikhonov، نويسنده , , Tatiana A. Babushkina، نويسنده , , Tamara P. Klimova، نويسنده , , Evgeniy V. Vorontsov، نويسنده , , Valery G. Babak، نويسنده , , Sergey A. Lopatin، نويسنده , , Igor A. Yamskov، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
8
From page
2414
To page
2421
Abstract
Regioselective quaternization of chitosan and its amphiphilic derivatives has been carried out by means of reaction with betaine in the presence of the coupling reagent 2-ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline (EEDQ) in aqueous media at pH 5.5 ± 0.5. This reaction results in preparation of N-/(trimethylammonio)acetyl/chitosan chloride and its amphiphilic derivatives. The degree of quaternization increases with increasing EEDQ/chitosan ratio and is partly accompanied by N-ethoxycarbonylation. That side-product formation can be minimized by increasing betaine/EEDQ ratio.
Keywords
Chitosan derivatives , quaternization , betaine , Chitosan , EEDQ
Journal title
European Polymer Journal(EPJ)
Serial Year
2007
Journal title
European Polymer Journal(EPJ)
Record number
1227205
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