Author/Authors :
Higashiyama، Shigeaki نويسنده Department of Nuclear medicine, Graduate School of Medicine, Osaka City University Higashiyama, Shigeaki , Kawabe ، Joji نويسنده Department of Nuclear medicine, Graduate School of Medicine, Osaka City University Kawabe , Joji , Yoshida، Atsushi نويسنده Department of Nuclear medicine, Graduate School of Medicine, Osaka City University Yoshida, Atsushi , Kotani، Kohei نويسنده Department of Nuclear medicine, Graduate School of Medicine, Osaka City University Kotani, Kohei , Shiomi، Susumu نويسنده Department of Nuclear medicine, Graduate School of Medicine, Osaka City University Shiomi, Susumu
Abstract :
We report a three-phase bone scintigraphy for the diagnosis of a peripheral bone lesion caused by systemic sarcoidosis. A 32-year-old man with suspected osteomyelitis of the right forefinger underwent three-phase bone scintigraphy with Tc-99m hydroxymethylene diphosphonate (HMDP) and single-photon emission computed tomography/computed tomography (SPECT/CT). The lesion was rich in blood flow according to flow study and blood pool study on bone scintigraphy, and was associated with an osteolytic change on SPECT/CT imaging performed 3 hours after injection of a radioisotope (RI). Whole-body bone scintigraphy indicated multiple high levels of abnormal RI accumulation.
The findings of the three-phase bone scintigraphy and SPECT/CT suggested the presence of systemic sarcoidosis; however, a subsequent 18Ffluorodeoxyglucose positron emission tomography/CT (FDG-PET/CT) could not exclude the possibility of multiple metastases from testicular tumors. Therefore, testicular enucleation was performed, and the pathological examination confirmed the presence of sarcoidosis.