Author/Authors :
Fathi، Fariba نويسنده Department of Chemistry , , Ektefa، Fatemeh نويسنده Department of Chemistry, Tarbiat Modares University, Tehran , , Tafazzoli، Mohsen نويسنده Department of Chemistry, Sharif University of Technology, Tehran , , Rostami، Kamran نويسنده Department of Gastroenterology, Mid Staffordshire NHS Foundation Trust, Stafford , , Fathi، Mohsen نويسنده , , Rezaye-Tavirani، Mostafa نويسنده , , Arefi Oskouie، Afsaneh نويسنده Department of Basic Science, Faculty of Paramedical Sciences , , Rostami Nejad، Mohammad نويسنده Gastroenterology and Liver Disease Research Center, Shahid Beheshti University of Medical Sciences, Tehran ,
Abstract :
Aim: This study evaluated serum levels of zinc in patient with CD compare to healthy subjects.
Background: Celiac disease (CD) is characterized by small intestinal malabsorption of nutrients as a consequence of ingestion of wheat gluten. Zinc is an essential trace element that it has vital biological functions.
Patients and methods: Sera of 30 celiac cases and 30 healthy normal cohorts as control group were obtained. Atomic absorption spectrophotometer was employed for estimating serum zinc level.
Results: Zinc concentrations in patients diagnosed with CD were significantly lower than healthy subjects (75.97±12 compared with 92.83±18, P-value < 0.0001).
Conclusion: The result of this study shows that serum zinc concentration is decreased in celiac patients compare to healthy controls. Serum zinc may thus be a marker of CD in adults presenting with gastrointestinal symptoms.
