Title of article
Rapid Kinetic Analysis of Transcription Elongation by Escherichia coli RNA Polymerase
Author/Authors
Ronald S. Johnson، نويسنده , , Mark Strausbauch، نويسنده , , Ryan Cooper، نويسنده , , J. Kristen Register، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
8
From page
1106
To page
1113
Abstract
Nucleotide incorporation during transcription by RNA polymerase is accompanied by pyrophosphate formation. Rapid release of pyrophosphate from the elongation complex at a rate consistent with productive transcription elongation occurs only in the presence of the correct next nucleotide for incorporation into the transcript.
Keywords
Transcription , translocation , RNA polymerase , pyrophosphate release , stopped-flow kinetics and quench-flow kinetics
Journal title
Journal of Molecular Biology
Serial Year
2008
Journal title
Journal of Molecular Biology
Record number
1257335
Link To Document