Fluorescence spectroscopy of a naturally occurring carbazole alkaloid: murrayanine

The fluorescence properties of a naturally occurring carbazole alkaloid, murrayanine, have been studied in various polar solvents and micellar systems. It was found that fluorescence peak position and intensity are extremely sensitive to the nature of the solvent medium. Murrayanine fluorescence has been further utilized to determine the critical micellization concentration of Pluronic F68, an amphiphilic copolymer with potential applications in drug-delivery. Time-resolved fluorescence and fluorescence anisotropy decay of murrayanine measured in several n-alcohols display a monotonic retardation with increasing chain-lengths of the alcohols.