Title of article :
Mammary tumor development is directly inhibited by lifelong n-3 polyunsaturated fatty acids
Author/Authors :
Mira B. MacLennan، نويسنده , , Shannon E. Clarke، نويسنده , , Kate Perez، نويسنده , , Geoffrey A. Wood، نويسنده , , William J. Muller، نويسنده , , Jing X. Kang، نويسنده , , David W.L. Ma، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2013
Abstract :
Mice expressing MMTV-neu(ndl)-YD5 and fat-1 displayed significant (P<.05) reductions in tumor volume (~30%) and multiplicity (~33%), as well as reduced n-6 PUFA and enriched n-3 PUFA in tumor phospholipids relative to MMTV-neu(ndl)-YD5 control mice. The effect observed in hybrid progeny was similarly observed in n-3 PUFA diet fed mice.
Keywords :
n-3 PUFA , Fat-1 mice , MMTV-neu(ndl)-YD5 mice , Mammary tumorigenesis , maternal nutrition , Breast cancer
Journal title :
The Journal of Nutritional Biochemistry
Journal title :
The Journal of Nutritional Biochemistry
