• Title of article

    Mammary tumor development is directly inhibited by lifelong n-3 polyunsaturated fatty acids

  • Author/Authors

    Mira B. MacLennan، نويسنده , , Shannon E. Clarke، نويسنده , , Kate Perez، نويسنده , , Geoffrey A. Wood، نويسنده , , William J. Muller، نويسنده , , Jing X. Kang، نويسنده , , David W.L. Ma، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2013
  • Pages
    8
  • From page
    388
  • To page
    395
  • Abstract
    Mice expressing MMTV-neu(ndl)-YD5 and fat-1 displayed significant (P<.05) reductions in tumor volume (~30%) and multiplicity (~33%), as well as reduced n-6 PUFA and enriched n-3 PUFA in tumor phospholipids relative to MMTV-neu(ndl)-YD5 control mice. The effect observed in hybrid progeny was similarly observed in n-3 PUFA diet fed mice.
  • Keywords
    n-3 PUFA , Fat-1 mice , MMTV-neu(ndl)-YD5 mice , Mammary tumorigenesis , maternal nutrition , Breast cancer
  • Journal title
    The Journal of Nutritional Biochemistry
  • Serial Year
    2013
  • Journal title
    The Journal of Nutritional Biochemistry
  • Record number

    1300145