Title of article
Anti-AIDS agents. Part 36: 17-carboxylated steroids as potential anti-HIV agents Original Research Article
Author/Authors
Peng-Xia Liu، نويسنده , , Zhengyu Yang، نويسنده , , Yi Xia، نويسنده , , Yun-Qing Zheng، نويسنده , , L. Mark Cosentino، نويسنده , , Kuo-Hsiung Lee، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
5
From page
1907
To page
1911
Abstract
In our search for novel anti-HIV agents, seven 17-carboxylated steroid derivatives were synthesized and evaluated as potential anti-HIV agents. Compound exhibited potent anti-HIV activity in acutely infected H9 lymphocytes with EC50 and therapeutic index values of 0.8 μM and 300, respectively.
Keywords
Anti-HIV , 17-carboxylated steroid
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1999
Journal title
Bioorganic and Medicinal Chemistry
Record number
1300478
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