Title of article
Synthesis and evaluation of pyrazolignans. A new class of cytotoxic agents Original Research Article
Author/Authors
Marina Gordaliza، نويسنده , , JoséM. Miguel del Corral، نويسنده , , M. Angeles Castro، نويسنده , , M. Luisa L?pez-V?zquez، نويسنده , , Arturo San Feliciano، نويسنده , , M. Dolores Garc?a-Gr?valos، نويسنده , , Alain Carpy، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
8
From page
1203
To page
1210
Abstract
A series of fused pyrazole derivatives of cyclolignans have been prepared through simple chemical routes and evaluated for their cytotoxic activities in culture cells of P-388 murine leukemia, A-549 lung carcinoma and HT-29 colon carcinoma. Despite the lack of the lactone moiety in their structures, they show IC50 values at μM levels.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1995
Journal title
Bioorganic and Medicinal Chemistry
Record number
1300522
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