Title of article :
Reversible modification of tissue-type plasminogen activator by methylphosphonate esters Original Research Article
Author/Authors :
In spite of their rapid aqueous hydrolysis، نويسنده , , 4-nitrophenyl 4-X-phenacyl methylphosphonates (X = H، نويسنده , , (PMN) CH3، نويسنده , , CH3O، نويسنده , , Cl and NO2) inactivate many serine proteases of the pancreatic and blood coagulation systems efficiently. The rate constants، نويسنده , , ki/Ki for the ، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Abstract :
Qinjian Zhao, Ildiko M Kovach
Keywords :
Fibrinolytic enzymes , serine protease inhibition , serine protease , t-PA inhibition , serine hydrolase inhibition
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry