Author/Authors :
Tian-Shung Wu، نويسنده , , Zhih-Jing Tsang، نويسنده , , Pei-Lin Wu، نويسنده , , Fuwen LIN، نويسنده , , Chia-Yin Li، نويسنده , , Che-Ming Teng، نويسنده , , Kuo-Hsiung Lee، نويسنده ,
Abstract :
Five new constituents including a flavonoid, artemisidin A (1), and four coumarins, artemicapins A (2), B (3), C (4) and D (5), together with 70 known compounds (6–75), have been isolated and characterized from the aerial part of Artemisia capillaris. The structures of these compounds were determined from spectral analyses and/or chemical evidence. Among them, 15 compounds (3, 6, 10, 18, 30–32, 38–41, 44, 45, 51, and 55) showed antiplatelet aggregation activity and three compounds (10, 17, and 51) demonstrated significant activity against HIV replication in H9 lymphocytic cells.