Title of article :
Azole derivatives of 1,4-benzothiazine as antifungal agents Original Research Article
Author/Authors :
Renata Fringuelli، نويسنده , , Fausto Schiaffella، نويسنده , , Francesco Bistoni، نويسنده , , Lucia Pitzurra، نويسنده , , Anna Vecchiarelli، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Abstract :
A series of azole derivatives of 1,4-benzothiazine 7–14 was synthesized and evaluated for the in vitro and in vivo activity against Candida albicans. Secondary alcohol 10 and its ether derivative 13 showed very good efficacy against systemic candidiasis in a murine experimental model.
Keywords :
Antifungal activity , Azole antifungals , 4-Benzothiazine , 1
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
