• Title of article

    Discovery of a novel lead structure for anti-malarials Original Research Article

  • Author/Authors

    Jochen Wiesner، نويسنده , , Pia Wi?ner، نويسنده , , Hans-Martin Dahse، نويسنده , , Hassan Jomaa، نويسنده , , Martin Schlitzer، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2001
  • Pages
    8
  • From page
    785
  • To page
    792
  • Abstract
    From a library of 61 compounds available from former studies 2,5-bis-acylaminobenzophenone 7p was identified as a lead structure for a novel class of anti-malaria agents active against multi-resistant Plasmodium falciparum strain Dd2. Some structural modifications of this initial lead demonstrated the potential for further improvement of the anti-plasmodial activity of this novel class of anti-malarials.
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Serial Year
    2001
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Record number

    1301444