Title of article
Catechol derivatives of aminopyrazine and cell protection against uvb-induced mortality Original Research Article
Author/Authors
Jean-François Cavalier، نويسنده , , Maggi Burton، نويسنده , , Frédérique Dussart، نويسنده , , Cécile Marchand، نويسنده , , Jean-François Rees، نويسنده , , Jacqueline Marchand-Brynaert، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
8
From page
1037
To page
1044
Abstract
A series of 5-aryl- and 3,5-bis-aryl-2-amino-1,4-pyrazine derivatives 4 and 6, and related imidazolopyrazinones 7, has been synthesized, the aryl groups of which are catechol and/or phenol substituents. These compounds, tested against human keratinocyte cells stressed by UVB irradiation, showed high antioxidative properties. One compound (6f) was more active than EGCG/ECG (green tea extract) in reducing cell mortality.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2001
Journal title
Bioorganic and Medicinal Chemistry
Record number
1301494
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