Author/Authors :
Heike Schürer، نويسنده , , Katherina Stembera، نويسنده , , Dietmar Knoll، نويسنده , , Günter Mayer، نويسنده , , Michael Blind، نويسنده , , Hans-Heinrich F?rster، نويسنده , , Michael Famulok، نويسنده , , Peter Welzel، نويسنده , , Ulrich Hahn، نويسنده ,
Abstract :
Nuclease-resistant moenomycin-binding aptamers with dissociation constants in the range of 300 to 400 nM have been selected. Competition experiments have demonstrated that these aptamers recognize a disaccharide analogue of moenomycin. The results offer the opportunity of setting up a selective and sensitive assay for identifying moenomycin biosynthetic precursors.
