Author/Authors :
Guido Barone، نويسنده , , Lorenzo De Napoli، نويسنده , , Giovanni Di Fabio، نويسنده , , Concetta Giancola، نويسنده , , Anna Messere، نويسنده , , Daniela Montesarchio، نويسنده , , Luigi Petraccone، نويسنده , , Gennaro Piccialli، نويسنده ,
Abstract :
Oligonucleotides with a 3′–3′ inversion of polarity site assured by one lysine residue have been synthesized, characterized and used as third strands in alternate strand triple helix formation. UV melting studies and molecular mechanics calculations have been carried out to investigate the stability and the geometry of these new triplexes.
