Title of article
Phenylpiperazinylmethylindolecarboxylates and derivatives as selective D4-Ligands Original Research Article
Author/Authors
Annette Moll، نويسنده , , Harald Hübner، نويسنده , , Peter Gmeiner، نويسنده , , Reinhard Troschütz، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
9
From page
1671
To page
1679
Abstract
Novel phenylpiperazinylmethylindolecarboxylates were synthesized for evaluation as potential D4-ligands. Test compounds showed high affinity for the human dopamine D4 receptor and great selectivity over the other receptor subtypes. Intrinsic effects of indole derivatives, which indicated most promising binding properties, were investigated in a mitogenesis assay.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2002
Journal title
Bioorganic and Medicinal Chemistry
Record number
1302096
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