Title of article
d-Glucosamine propanedithioacetal, an efficient chiral auxiliary in β-Lactam chemistry Original Research Article
Author/Authors
Josefa Anaya، نويسنده , , Stéphane Dov Gero، نويسنده , , Manuel Grande، نويسنده , , José Ignacio M Hernando، نويسنده , , Nieves M Laso، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
14
From page
837
To page
850
Abstract
The synthesis of some monocyclic β-lactams (monobactams) by the Staudinger reaction using d-glucosamine propanedithioacetal as chiral auxiliary is reported. The influence of several radicals at C3, C4, and C1′ (sugar moiety) as well as other structural aspects are considered in relation to the antielastase activity.
Keywords
Synthesis , structure/circular dichroism , antielastase activity , ?-Lactams
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1999
Journal title
Bioorganic and Medicinal Chemistry
Record number
1302288
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