Title of article
Imidazothiadiazine dioxides: synthesis and antiviral activity Original Research Article
Author/Authors
Ana Martinez، نويسنده , , Ana I. Esteban، نويسنده , , Angela Herrero، نويسنده , , Carmen Ochoa، نويسنده , , Graciela Andrei، نويسنده , , Robert Snoeck، نويسنده , , Jan Balzarini، نويسنده , , Erik De Clercq، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
7
From page
1617
To page
1623
Abstract
A new series of imidazothiadiazine dioxides, including the first acyclonucleosides derived from this heterocycle moiety, has been synthesized. A wide-spectrum antiviral screening was performed. Some of the N-1 benzyl imidazothiadiazines and the new acyclonucleosides showed interesting anti-CMV or anti-HIV activity. These structures could be considered as new lead compounds for antiviral drug research.
Keywords
Imidazothiadiazine , HIV , acyclonucleoside , Antiviral , CMV
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1999
Journal title
Bioorganic and Medicinal Chemistry
Record number
1302369
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