Author/Authors :
Junko Ishida، نويسنده , , Hironori Ohtsu، نويسنده , , Yoko Tachibana، نويسنده , , Yuka Nakanishi، نويسنده , , Kenneth F. Bastow، نويسنده , , Masahiro Nagai، نويسنده , , Hui-Kang Wang، نويسنده , , Hideji Itokawa، نويسنده , , Kuo-Hsiung Lee، نويسنده ,
Abstract :
Fifty-eight curcumin analogues were prepared and evaluated for in vitro cytotoxicity against a panel of human tumor cell lines. Compound was the most potent analogue against several cell lines, including HOS (bone cancer) and 1A9 (breast cancer), with ED50 values of 0.97 and <0.63 μg/mL, respectively.
