Title of article
Catechols from abietic acid: synthesis and evaluation as bioactive compounds Original Research Article
Author/Authors
B Gigante، نويسنده , , C Santos، نويسنده , , Clarysson A.M. Silva، نويسنده , , M.J.M Curto، نويسنده , , M.S.J Nascimento، نويسنده , , E Pinto، نويسنده , , M Pedro، نويسنده , , F Cerqueira، نويسنده , , Madalena M.M. Pinto، نويسنده , , M.P. Duarte، نويسنده , , A Laires، نويسنده , , J Rueff، نويسنده , , J Gonçalves، نويسنده , , M.I Pegado، نويسنده , , M.L Valdeira، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
8
From page
1631
To page
1638
Abstract
Catechols from abietic acid were prepared by a short and good yielding chemical process and further evaluated for several biological activities namely, antifungal, antitumoral, antimutagenic, antiviral, antiproliferative and inhibition of nitric oxide. Their properties were compared with those of carnosic acid (6), a naturally occurring catechol with an abietane skeleton and known to possess potent antioxidant activity, as well as anticancer and antiviral properties. From all the synthetic catechols tested compound 2 showed the best activities, stronger than carnosic acid.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2003
Journal title
Bioorganic and Medicinal Chemistry
Record number
1302649
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