Author/Authors :
Hea-Young Park Choo، نويسنده , , Suyoung Choi، نويسنده , , Chung-Kyu Ryu، نويسنده , , Hwa-Jung Kim، نويسنده , , In Young Lee، نويسنده , , Ae Nim Paeb، نويسنده , , Hun Yeong Koh، نويسنده ,
Abstract :
The 3D-QSAR study of quinolinediones which showed potent inhibitory effect on the acetylcholine induced vasorelaxation of rat aorta with the endothelium was conducted by CoMSIA. The statistical result, cross-validated q2 (0.741) and r2 (0.960) values, gave reliability to the prediction of inhibitory activity of this series.
