Author/Authors :
Shengmin Sang، نويسنده , , Guangming Liu، نويسنده , , Kan He، نويسنده , , Nanqun Zhu، نويسنده , , Zigang Dong، نويسنده , , Qunyi Zheng، نويسنده , , Robert T Rosen، نويسنده , , Chi-Tang Ho، نويسنده ,
Abstract :
A novel iridoid dimer in whose structure the two iridoid units are connected by a rare ether group, together with two new unusual iridoids showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, have been isolated from the leaves of noni (Morinda citrifolia L.). Their structures were determined on the basis of detailed high-field 1D and 2D spectral analysis. Their inhibitory effect on UVB-induced transcriptional Activator Protein-1 (AP-1) activity are also discussed.
