Title of article
Remarkable G2/M phase arrest and apoptotic effect performed by 2-(6-aryl-3-hexen-1,5-diynyl) benzonitrile antitumor agents Original Research Article
Author/Authors
Yu-Hsiang Lo، نويسنده , , Chi-Fong Lin، نويسنده , , Ming-Chu Hsieh، نويسنده , , Ming-Jung Wu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
7
From page
1047
To page
1053
Abstract
2-(6-aryl-3-hexen-1,5-diynyl)benzonitriles 3a–j showed growth inhibition effects on a full panel of 60 human cancer cell lines in low micro-concentrations, in which compounds 3c,d displayed a significant G2/M arrest in the cell growth cycle compared with other derivatives and an apoptotic progress induction were also shown by 3a–d.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2004
Journal title
Bioorganic and Medicinal Chemistry
Record number
1302936
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