Title of article
Natural product glycorandomization
Author/Authors
Jie Yang، نويسنده , , Dirk Hoffmeister، نويسنده , , Lesley Liu، نويسنده , , Xun Fu، نويسنده , , Jon S. Thorson، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
8
From page
1577
To page
1584
Abstract
Glycorandomization is a chemoenzymatic strategy that overcomes the limitations in natural product derivatization associated with both solely chemistry-based approaches or in vivo engineering. In this article we present the basic strategies for glycorandomization development as a next-generation tool in drug discovery.
Keywords
Glycosyltransferase , Enzyme catalysis , Galactokinase , Nucleotidylyltransferase , Natural products , Antibiotics
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2004
Journal title
Bioorganic and Medicinal Chemistry
Record number
1302978
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