Author/Authors :
Bipul Baruah، نويسنده , , Kavitha Dasu، نويسنده , , Balasubramanian Vaitilingam، نويسنده , , Premkumar Mamnoor، نويسنده , , Prasanthi Penubaka Venkata، نويسنده , , Sriram Rajagopal، نويسنده , , Koteswar Rao Yeleswarapu، نويسنده ,
Abstract :
A novel series of quinazolino-β-carbolinone derivatives was synthesized and evaluated for their in vitro and in vivo anticancer activity. Many compounds have shown good in vitro activity in the range 1–8 μM concentration. Three of the compounds were further tested in nude mice bearing HT-29 colon cancer xenografts.
