Title of article
Synthesis of new 2-arylamino-6-trifluoromethylpyridine-3-carboxylic acid derivatives and investigation of their analgesic activity Original Research Article
Author/Authors
Maria T. Cocco، نويسنده , , Cenzo Congiu، نويسنده , , Valentina Onnis، نويسنده , , Micaela Morelli، نويسنده , , Vicente Felipo، نويسنده , , Omar Cauli، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
9
From page
4169
To page
4177
Abstract
A new series of 2-arylamino-6-trifluoromethyl-3-carboxylic acid derivatives was synthesized and assayed in vivo for their analgesic properties by means of writhing test in rats. When compared to aspirin, ibuprofen and flufenamic acid some of the new compounds exhibited a comparable or improved analgesic activity and a lower ulcerogenic effect.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2004
Journal title
Bioorganic and Medicinal Chemistry
Record number
1303197
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