Title of article
New broad-spectrum parenteral cephalosporins exhibiting potent activity against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Part 2: Synthesis and structure–activity relationships in the S-3578 series Original Resear
Author/Authors
Hidenori Yoshizawa، نويسنده , , Tadatoshi Kubota، نويسنده , , Hikaru Itani، نويسنده , , Hiroyuki Ishitobi، نويسنده , , Hideaki Miwa، نويسنده , , Yasuhiro Nishitani، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
9
From page
4211
To page
4219
Abstract
Among the prepared novel cephalosporin derivatives related to S-3578, a series of 7β-[2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-ethoxyiminoacetamido]-3-[1-(aminoalkyl)-1H-pyrazolo[4,3-b]pyridinium-4-yl]methyl-3-cephem-4-carboxylate showed potent activity against both MRSA and Pseudomonas aeruginosa, and displayed good water solubility.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2004
Journal title
Bioorganic and Medicinal Chemistry
Record number
1303201
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