Title of article
Synthesis and DNA binding affinity of novel A-C8/C-C2-exo unsaturated alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers Original Research Article
Author/Authors
Ahmed Kamal، نويسنده , , O Srinivas، نويسنده , , P Ramulu، نويسنده , , G Ramesh، نويسنده , , P.Praveen Kumar، نويسنده , , M.Shiva Kumar، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
14
From page
4337
To page
4350
Abstract
The synthesis of novel A-C8/C-C2-exo unsaturated alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers is reported and these dimers show significant DNA binding affinity and they also exhibit moderate anticancer activity.
Keywords
DNA binding affinity , Cytotoxicity , Pyrrolobenzodiazepine dimers
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2004
Journal title
Bioorganic and Medicinal Chemistry
Record number
1303211
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