Title of article :
Novel tetrahydro-thieno pyridyl oxazolidinone: an antibacterial agent Original Research Article
Author/Authors :
Braj Bhushan Lohray، نويسنده , , Vidya Bhushan Lohray، نويسنده , , Brijesh Kumar Srivastava، نويسنده , , Prashant B. Kapadnis، نويسنده , , Purvi Pandya، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
Synthesis of a number of 4,5,6,7-tetrahydro-thieno[3,2-c]pyridine substituted oxazolidinones have been reported. They have been screened against a panel of Gram-positive pathogens including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis. A SAR has been developed. Compound 15 showed comparable activity (MIC) to linezolid and superior to eperezolid.
Keywords :
Oxazolidinone , 4 , 5 , 2-c]pyridine , 6 , in vitro activity , Linezolid
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
