Molluscicidal activity of synthetic lapachol amino and hydrogenated derivatives Original Research Article

A series of new amino derivatives and a new partially hydrogenated derivative of the natural naphthoquinone lapachol were assayed for molluscicidal activity against Biomphalaria glabrata. These derivatives showed low to medium LC50 values, and a 3.1 μg/mL value for the most potent derivative of the series. The toxicity is in agreement with the decrease of polar character of the tested compounds.