• Title of article

    Molluscicidal activity of synthetic lapachol amino and hydrogenated derivatives Original Research Article

  • Author/Authors

    Tania M.S. Silva، نويسنده , , Celso A. Camara، نويسنده , , Ticiano P. Barbosa، نويسنده , , André Z. Soares، نويسنده , , Luciana C. da Cunha، نويسنده , , Angelo C. Pinto، نويسنده , , Maria D. Vargas، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    4
  • From page
    193
  • To page
    196
  • Abstract
    A series of new amino derivatives and a new partially hydrogenated derivative of the natural naphthoquinone lapachol were assayed for molluscicidal activity against Biomphalaria glabrata. These derivatives showed low to medium LC50 values, and a 3.1 μg/mL value for the most potent derivative of the series. The toxicity is in agreement with the decrease of polar character of the tested compounds.
  • Keywords
    lapachol , Molluscicide , naphthoquinones
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Serial Year
    2005
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Record number

    1303469