Title of article :
Monometallic complexes of 1,4,7,10-tetraazacyclododecane containing an imidazolium side: Synthesis, characterization, and their interaction with plasmid DNA Original Research Article
Author/Authors :
Qiang-Lin Li، نويسنده , , Jun Huang، نويسنده , , Qin Wang، نويسنده , , Ning Jiang، نويسنده , , Chuanqin Xia، نويسنده , , Hong-Hui Lin، نويسنده , , Jiang Wu، نويسنده , , Xiao-Qi Yu، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
The synthesis of macrocyclic polyamine monometallic complexes containing imidazolium salt groups was reported. Their interaction with pUC19 plasmid DNA was studied. The result showed that these complexes can catalyze the DNA cleavage with unprecedented reactivity under physiological conditions.
Keywords :
1 , 7 , 4 , 10-Tetraazacyclododecane (cyclen) , Macrocyclic polyamine , Imidazolium salt , Monometallic complex , Synthesis , pUC19 DNA , Cleavage
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
