Title of article
Synthesis and antiviral activities of novel chiral cyanoacrylate derivatives with (E) configuration Original Research Article
Author/Authors
Zhuo Chen، نويسنده , , Xianyou Wang، نويسنده , , Baoan Song، نويسنده , , Hua Wang، نويسنده , , Pinaki S. Bhadury، نويسنده , , Kai-Yan Gao، نويسنده , , Huiping Zhang، نويسنده , , Song Yang، نويسنده , , Linhong Jin، نويسنده , , Deyu Hu، نويسنده , , Wei Xue، نويسنده , , He-Song Zeng، نويسنده , , Jun Wang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
8
From page
3076
To page
3083
Abstract
The intermediate 3 is converted by the nucleophilic attack of the appropriate aryl (heterocyclic) amine under microwave irradiation into the chiral (E) isomers of title compound 4. These compounds exhibited weak to good anti-TMV bioactivity with (R)-4p showing significant enhancement of disease resistance in tobacco leaves.
Keywords
3076-3083
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2008
Journal title
Bioorganic and Medicinal Chemistry
Record number
1304141
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