Title of article
Investigating biological activity spectrum for novel quinoline analogues 2: Hydroxyquinolinecarboxamides with photosynthesis-inhibiting activity Original Research Article
Author/Authors
Robert Musiol، نويسنده , , Dominik Tabak، نويسنده , , Halina Niedbala، نويسنده , , Barbara Podeszwa، نويسنده , , Josef Jampilek، نويسنده , , Katarina Kralova، نويسنده , , Jiri Dohnal، نويسنده , , Jacek Finster، نويسنده , , Agnieszka Mencel، نويسنده , , Jaroslaw Polanski، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
10
From page
4490
To page
4499
Abstract
Two series of amides based on quinoline scaffold were designed and synthesized in search of photosynthesis inhibitors. The compounds were tested for their photosynthesis-inhibiting activity against Spinacia oleracea L. and Chlorella vulgaris Beij. The compounds lipophilicity was determined by the RP-HPLC method. Several compounds showed biological activity similar or even higher than that of the standard (DCMU). The structure–activity relationships are discussed.
Keywords
Lipophilicity , PET inhibition , Spinach chloroplasts , Chlorophyll , Chlorella vulgaris , Quinoline derivatives
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2008
Journal title
Bioorganic and Medicinal Chemistry
Record number
1304272
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