Title of article
An improved synthesis of arsenic–biotin conjugates Original Research Article
Author/Authors
Jorge Heredia-Moya، نويسنده , , Kenneth L. Kirk، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
4
From page
5743
To page
5746
Abstract
An amide linked conjugate of p-aminophenylarsine oxide and biotin is conveniently prepared in a one-pot procedure by the reaction of biotinyl chloride, formed in situ, with p-aminophenyldichloroarsine. The reaction of the arsine oxide–biotin conjugate with 1,2-ethanedithiol produces the stabilized dithiarsolane. These reagents are now readily available for a variety of applications.
Keywords
Arsenic , Biotin , Avidin , Conjugates
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2008
Journal title
Bioorganic and Medicinal Chemistry
Record number
1304380
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