Title of article
Dihydropyrido[2,3-d]pyrimidines as a new class of antileishmanial agents Original Research Article
Author/Authors
Anu Agarwal، نويسنده , , Ramesh، نويسنده , , Ashutosh، نويسنده , , Neena Goyal، نويسنده , , Prem M.S. Chauhan، نويسنده , , Suman Gupta، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
7
From page
6678
To page
6684
Abstract
A series of dihydropyrido[2,3-d]pyrimidines have been synthesized and screened for its in vitro antileishmanial activity profile in promastigote and amastigote models. Compounds 2a–2l have shown 83–100% inhibition against promastigotes and 79–100% inhibition against amastigotes at a concentration of 50 μg/mL.
Keywords
Lieshmania , 3-d]pyrimidine , dihydrofolate reductase , Uracil
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2005
Journal title
Bioorganic and Medicinal Chemistry
Record number
1305018
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