Title of article :
Synthesis of verbenachalcone congeners and their biological assessment against activation of the NGF-mediated neurite outgrowth of PC12D cells’ activity Original Research Article
Author/Authors :
Takamasa Tanabe، نويسنده , , Takahisa Ogamino، نويسنده , , Yoshifumi Shimizu، نويسنده , , Masaya Imoto، نويسنده , , Shigeru Nishiyama، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
Synthesis of the verbenachalcone derivatives 3–5 involving littorachalcone 2 from diaryl ether 7 enabled an SAR study of enhancement activity against the NGF-mediated neurite outgrowth from PC12D cells. Littorachalcone 2 and o-deoxyverbenachalcone 5 showed similar activity to that of verbenachalcone 1.
Keywords :
NGF-mediated neurite outgrowth , Verbena littoralis , verbenachalcone , Littorachalcone , Anodic oxidation
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
