Title of article :
Study on the compounds containing 19F and 10B atoms in a single molecule for the application to MRI and BNCT Original Research Article
Author/Authors :
Yoshihide Hattori، نويسنده , , Tomoyuki Asano، نويسنده , , Yoko Niki، نويسنده , , Hirofumi Kondoh، نويسنده , , Mitsunori Kirihata، نويسنده , , Yoshihiro Yamaguchi، نويسنده , , Tateaki Wakamiya، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
Magnetic resonance imaging (MRI) and boron-neutron capture therapy (BNCT) are quite attractive techniques for diagnosis and treatment of cancer, respectively. In order to progress the study on both MRI and BNCT, the novel compounds containing 19F and 10B atoms in a single molecule were designed and synthesized. In the present paper, the syntheses and the internalization rates into tumor cells of these compounds are elucidated.
Keywords :
Magnetic resonance imaging , Boron-neutron capture therapy , 6-difluorophenyl]-alanine , ?-1 , 6-difluorophenyl]alaninol , ?-1
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry