Title of article :
Alpneumines A–H, new anti-melanogenic indole alkaloids from Alstonia pneumatophora Original Research Article
Author/Authors :
Koichiro Koyama، نويسنده , , Yusuke Hirasawa، نويسنده , , Takahiro Hosoya، نويسنده , , Teh Chin Hoe، نويسنده , , Kit-Lam Chan، نويسنده , , Hiroshi Morita، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2010
Abstract :
Eight new indole alkaloids, alpneumines A–H (1–8) were isolated from the Malaysian Alstonia pneumatophora (Apocynaceae) and their structures were determined by MS and 2D NMR spectroscopic methods. Alpneumines E and G (5 and 7), vincamine, and apovincamine showed anti-melanogenesis in B16 mouse melanoma cells.
Keywords :
Alkaloids , Alstonia pneumatophora , Alpneumines A–H , Anti-melanogenesis
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry