Title of article :
An endoplasmic reticulum (ER) stress-suppressive compound and its analogues from the mushroom Hericium erinaceum Original Research Article
Author/Authors :
Keiko Ueda، نويسنده , , Megumi Tsujimori، نويسنده , , Shinya Kodani، نويسنده , , Akiko Chiba، نويسنده , , Masakazu Kubo، نويسنده , , Kazuhiko Masuno، نويسنده , , Atsushi Sekiya، نويسنده , , Kaoru Nagai، نويسنده , , Hirokazu Kawagishi، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Abstract :
Three new compounds, 3-hydroxyhericenone F (1), hericenone I (2), and hericenone J (3), were isolated from the mushroom Hericium erinaceum. The structures of 1–3 were determined by the interpretation of spectral data. Compound 1 showed the protective activity against endoplasmic reticulum (ER) stress-dependent Neuro2a cell death, however, compounds 2 and 3 did not.
Keywords :
Neurodegenerative disease , Mushroom , Hericium erinaceum , Endoplasmic reticulum stress suppression , Hericenone
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
