Comparison of dissolution resistance in artificial hydroxyapatite and biologically derived hydroxyapatite ceramics Original Research Article

Dissolving behavior of hydroxyapatite (HA) ceramics prepared from bovine bones (BHA) was investigated and compared with artificial HA. BHA and artificial HA were sintered at 1200 °C for 1 h, and they were immersed in distilled water at 37 °C for 3, 7, 14 and 28 days. Detectable peaks in artificial HA were only identical to HA phase, however, BHA consists of mostly HA phase and small amount of MgO. Sintered density of BHA was lower than that of artificial HA. Dissolution of artificial HA was founded after 7 days. The grain boundaries on the surface of artificial HA appeared to initiate dissolution, and grains are pulled out of the artificial HA surface at the end of the immersion period, however, there is no evidence of BHA surface at the end of the immersion period. It was found that HA from bovine bone was more stable than artificial HA in a liquid environment.